Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 1
Ligand
BDBM58193
Substrate
n/a
Meas. Tech.
Fluorescence-based counterscreen for potentiators or agonists of NPY-Y2: cell-based high-throughput dose response assay for potentiators or agonists of NPY-Y1.
EC50
11218±n/a nM
Citation
PubChem, PC Fluorescence-based counterscreen for potentiators or agonists of NPY-Y2: cell-based high-throughput dose response assay for potentiators or agonists of NPY-Y1. PubChem Bioassay (2009)[AID]
More Info.:
Target
Name:
Neuropeptide Y receptor type 1
Synonyms:
NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44399.07
Organism:
Homo sapiens (Human)
Description:
NPY-Y1 NPY1R HUMAN::P25929
Residue:
384
Sequence:
MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEKI
Inhibitor
Name:
BDBM58193
Synonyms:
1-(3,4-dichlorophenyl)-3-[2-[2,6-dinitro-4-(trifluoromethyl)anilino]ethyl]thiourea | 1-(3,4-dichlorophenyl)-3-[2-[[2,6-dinitro-4-(trifluoromethyl)phenyl]amino]ethyl]thiourea | MLS000833819 | N-(3,4-dichlorophenyl)-N'-{2-[2,6-dinitro-4-(trifluoromethyl)anilino]ethyl}thiourea | SMR000457540 | cid_2803877
Type:
Small organic molecule
Emp. Form.:
C16H12Cl2F3N5O4S
Mol. Mass.:
498.264
SMILES:
[O-][N+](=O)c1cc(cc(c1NCCNC(=S)Nc1ccc(Cl)c(Cl)c1)[N+]([O-])=O)C(F)(F)F