Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 1
Ligand
BDBM48527
Substrate
n/a
Meas. Tech.
Fluorescence-based counterscreen for agonists of NPY-Y2: cell-based high-throughput dose response assay for agonists of NPY-Y1.
EC50
3068±n/a nM
Citation
 PubChem, PC Fluorescence-based counterscreen for agonists of NPY-Y2: cell-based high-throughput dose response assay for agonists of NPY-Y1. PubChem Bioassay (2009)[AID] 
Target
Name:
Neuropeptide Y receptor type 1
Synonyms:
NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44399.07
Organism:
Homo sapiens (Human)
Description:
NPY-Y1 NPY1R HUMAN::P25929
Residue:
384
Sequence:
MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEKI
  
Inhibitor
Name:
BDBM48527
Synonyms:
1-(3-methylphenyl)-2,3-dihydropyrrolo[2,3-b]quinolin-4-amine;oxalic acid | 1-m-Tolyl-2,3-dihydro-1H-pyrrolo[2,3-b]quinolin-4-ylamine | MLS000068712 | SMR000009331 | [1-(m-tolyl)-2,3-dihydropyrrolo[2,3-b]quinolin-4-yl]amine;hydrochloride | [1-(m-tolyl)-2,3-dihydropyrrolo[2,3-b]quinolin-4-yl]amine;oxalic acid | cid_653126 | ethanedioic acid;1-(3-methylphenyl)-2,3-dihydropyrrolo[2,3-b]quinolin-4-amine
Type:
Small organic molecule
Emp. Form.:
C18H17N3
Mol. Mass.:
275.3477
SMILES:
Cc1cccc(c1)N1CCc2c1nc1ccccc1c2N
Structure:
Search PDB for entries with ligand similarity: