Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 1
Ligand
BDBM61841
Substrate
n/a
Meas. Tech.
Fluorescence-based counterscreen for agonists of NPY-Y2: cell-based high-throughput dose response assay for agonists of NPY-Y1.
EC50
>35430±n/a nM
Citation
 PubChem, PC Fluorescence-based counterscreen for agonists of NPY-Y2: cell-based high-throughput dose response assay for agonists of NPY-Y1. PubChem Bioassay (2009)[AID] 
Target
Name:
Neuropeptide Y receptor type 1
Synonyms:
NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44399.07
Organism:
Homo sapiens (Human)
Description:
NPY-Y1 NPY1R HUMAN::P25929
Residue:
384
Sequence:
MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEKI
  
Inhibitor
Name:
BDBM61841
Synonyms:
(Z)-3-(1-Acetyl-1H-indol-3-yl)-2-nitro-acrylic acid methyl ester | (Z)-3-(1-acetyl-3-indolyl)-2-nitro-2-propenoic acid methyl ester | (Z)-3-(1-acetylindol-3-yl)-2-nitro-acrylic acid methyl ester | MLS001012372 | SMR000426886 | cid_1910983 | methyl (Z)-3-(1-acetylindol-3-yl)-2-nitroprop-2-enoate | methyl (Z)-3-(1-ethanoylindol-3-yl)-2-nitro-prop-2-enoate
Type:
Small organic molecule
Emp. Form.:
C14H12N2O5
Mol. Mass.:
288.2555
SMILES:
COC(=O)C(=C\c1cn(C(C)=O)c2ccccc12)\[N+]([O-])=O
Structure:
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