Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 1
Ligand
BDBM58070
Substrate
n/a
Meas. Tech.
Fluorescence-based counterscreen for agonists of NPY-Y2: cell-based high-throughput dose response assay for agonists of NPY-Y1.
EC50
>35430±n/a nM
Citation
 PubChem, PC Fluorescence-based counterscreen for agonists of NPY-Y2: cell-based high-throughput dose response assay for agonists of NPY-Y1. PubChem Bioassay (2009)[AID] 
Target
Name:
Neuropeptide Y receptor type 1
Synonyms:
NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44399.07
Organism:
Homo sapiens (Human)
Description:
NPY-Y1 NPY1R HUMAN::P25929
Residue:
384
Sequence:
MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEKI
  
Inhibitor
Name:
BDBM58070
Synonyms:
2-[(E)-[3-(3-methoxypropyl)-4-oxidanylidene-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl]-5-[(4-methylphenyl)amino]-1,3-oxazole-4-carbonitrile | 2-[(E)-[3-(3-methoxypropyl)-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl]-5-(4-methylanilino)-1,3-oxazole-4-carbonitrile | 2-[(E)-[3-(3-methoxypropyl)-4-oxo-2-sulfanylidene-5-thiazolidinylidene]methyl]-5-(4-methylanilino)-4-oxazolecarbonitrile | 2-[(E)-[4-keto-3-(3-methoxypropyl)-2-thioxo-thiazolidin-5-ylidene]methyl]-5-(p-toluidino)oxazole-4-carbonitrile | 2-[3-(3-Methoxy-propyl)-4-oxo-2-thioxo-thiazolidin-(5E)-ylidenemethyl]-5-p-tolylamino-oxazole-4-carbon itrile | MLS000333371 | SMR000436724 | cid_2026614
Type:
Small organic molecule
Emp. Form.:
C19H18N4O3S2
Mol. Mass.:
414.501
SMILES:
COCCCN1C(=S)S\C(=C\c2nc(C#N)c(Nc3ccc(C)cc3)o2)C1=O
Structure:
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