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Target
Neuropeptide Y receptor type 2
Ligand
BDBM61778
Substrate
n/a
Meas. Tech.
Fluorescence-based counterscreen for agonists of NPY-Y1: cell-based high-throughput dose response assay for agonists of NPY-Y2.
EC50
12439±n/a nM
Citation
 PubChem, PC Fluorescence-based counterscreen for agonists of NPY-Y1: cell-based high-throughput dose response assay for agonists of NPY-Y2. PubChem Bioassay (2009)[AID] 
Target
Name:
Neuropeptide Y receptor type 2
Synonyms:
NPY-Y2 | NPY-Y2 receptor | NPY2-R | NPY2R | NPY2R_HUMAN | Neuropeptide Y receptor type 2 | Y2 receptor | neuropeptide Y receptor Y2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42734.65
Organism:
Homo sapiens (Human)
Description:
NPY-Y2 NPY2R HUMAN::P49146
Residue:
381
Sequence:
MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
  
Inhibitor
Name:
BDBM61778
Synonyms:
2-benzyl-3-[4-(diethylamino)anilino]-3-keto-propionic acid ethyl ester | 3-[4-(diethylamino)anilino]-3-oxo-2-(phenylmethyl)propanoic acid ethyl ester | MLS000573081 | SMR000185011 | cid_2836861 | ethyl 2-benzyl-3-[4-(diethylamino)anilino]-3-oxopropanoate | ethyl 2-benzyl-3-{[4-(diethylamino)phenyl]amino}-3-oxopropanoate | ethyl 3-[[4-(diethylamino)phenyl]amino]-3-oxidanylidene-2-(phenylmethyl)propanoate
Type:
Small organic molecule
Emp. Form.:
C22H28N2O3
Mol. Mass.:
368.4693
SMILES:
CCOC(=O)C(Cc1ccccc1)C(=O)Nc1ccc(cc1)N(CC)CC
Structure:
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