Reaction Details Report a problem with these data
Target
Phosphotransferase
Ligand
BDBM62035
Substrate
n/a
Meas. Tech.
Confirmation assay for inhibitors of Trypanosoma brucei hexokinase 1-Analogue-first series
IC50
9430±n/a nM
Citation
 PubChem, PC Confirmation assay for inhibitors of Trypanosoma brucei hexokinase 1-Analogue-first series PubChem Bioassay (2010)[AID] 
Target
Name:
Phosphotransferase
Synonyms:
hexokinase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51160.00
Organism:
Trypanosoma brucei
Description:
gi_70832125
Residue:
471
Sequence:
MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFDFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVATMISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPISMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAVLAKGGSGVGAALISAIVADGK
  
Inhibitor
Name:
BDBM62035
Synonyms:
2-(1,3-benzodioxol-5-ylcarbonylamino)-4-chloranyl-benzoic acid | 2-(1,3-benzodioxole-5-carbonylamino)-4-chlorobenzoic acid | 2-[[1,3-benzodioxol-5-yl(oxo)methyl]amino]-4-chlorobenzoic acid | 4-chloro-2-(piperonyloylamino)benzoic acid | KSC-09-199B | KUC106004N | cid_16777892
Type:
Small organic molecule
Emp. Form.:
C15H10ClNO5
Mol. Mass.:
319.697
SMILES:
OC(=O)c1ccc(Cl)cc1NC(=O)c1ccc2OCOc2c1
Structure:
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