Reaction Details Report a problem with these data
Target
Neuropeptides B/W receptor type 1
Ligand
BDBM62067
Substrate
n/a
Meas. Tech.
Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7).
IC50
43807±n/a nM
Citation
 PubChem, PC Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7). PubChem Bioassay (2010)[AID] 
Target
Name:
Neuropeptides B/W receptor type 1
Synonyms:
GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36111.82
Organism:
Homo sapiens (Human)
Description:
gi_119607128
Residue:
328
Sequence:
MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
  
Inhibitor
Name:
BDBM62067
Synonyms:
MLS000044184 | N-[1-(cyclopentylcarbamoyl)cyclohexyl]-N-(oxolan-2-ylmethyl)-1,3-benzodioxole-5-carboxamide | N-[1-(cyclopentylcarbamoyl)cyclohexyl]-N-(tetrahydrofurfuryl)-piperonylamide | N-[1-[(cyclopentylamino)-oxomethyl]cyclohexyl]-N-(2-oxolanylmethyl)-1,3-benzodioxole-5-carboxamide | N-{1-[(cyclopentylamino)carbonyl]cyclohexyl}-N-(tetrahydrofuran-2-ylmethyl)-1,3-benzodioxole-5-carboxamide | SMR000021968 | cid_3241540
Type:
Small organic molecule
Emp. Form.:
C25H34N2O5
Mol. Mass.:
442.5479
SMILES:
O=C(NC1CCCC1)C1(CCCCC1)N(CC1CCCO1)C(=O)c1ccc2OCOc2c1
Structure:
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