Reaction Details Report a problem with these data
Target
Neuropeptides B/W receptor type 1
Ligand
BDBM62071
Substrate
n/a
Meas. Tech.
Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7).
IC50
43807±n/a nM
Citation
 PubChem, PC Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7). PubChem Bioassay (2010)[AID] 
Target
Name:
Neuropeptides B/W receptor type 1
Synonyms:
GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36111.82
Organism:
Homo sapiens (Human)
Description:
gi_119607128
Residue:
328
Sequence:
MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
  
Inhibitor
Name:
BDBM62071
Synonyms:
MLS000062566 | N-(2-furanylmethyl)-1-(4-methoxyphenyl)sulfonyl-4-piperidinecarboxamide | N-(2-furfuryl)-1-(4-methoxyphenyl)sulfonyl-isonipecotamide | N-(2-furylmethyl)-1-[(4-methoxyphenyl)sulfonyl]-4-piperidinecarboxamide | N-(furan-2-ylmethyl)-1-(4-methoxyphenyl)sulfonyl-piperidine-4-carboxamide | N-(furan-2-ylmethyl)-1-(4-methoxyphenyl)sulfonylpiperidine-4-carboxamide | SMR000071576 | cid_1081777
Type:
Small organic molecule
Emp. Form.:
C18H22N2O5S
Mol. Mass.:
378.443
SMILES:
COc1ccc(cc1)S(=O)(=O)N1CCC(CC1)C(=O)NCc1ccco1
Structure:
Search PDB for entries with ligand similarity: