Target
Neuropeptides B/W receptor type 1
Ligand
BDBM62075
Substrate
n/a
Meas. Tech.
Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7).
IC50
43807±n/a nM
Citation
 PubChem, PC Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7). PubChem Bioassay (2010)[AID] 
Target
Name:
Neuropeptides B/W receptor type 1
Synonyms:
GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36111.82
Organism:
Homo sapiens (Human)
Description:
gi_119607128
Residue:
328
Sequence:
MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
  
Inhibitor
Name:
BDBM62075
Synonyms:
5-amino-N-(2,4-dimethoxyphenyl)-1-(4-ethylbenzyl)triazole-4-carboxamide | 5-amino-N-(2,4-dimethoxyphenyl)-1-[(4-ethylphenyl)methyl]-4-triazolecarboxamide | 5-amino-N-(2,4-dimethoxyphenyl)-1-[(4-ethylphenyl)methyl]triazole-4-carboxamide | 5-azanyl-N-(2,4-dimethoxyphenyl)-1-[(4-ethylphenyl)methyl]-1,2,3-triazole-4-carboxamide | MLS000117997 | SMR000094945 | cid_5309186
Type:
Small organic molecule
Emp. Form.:
C20H23N5O3
Mol. Mass.:
381.4283
SMILES:
CCc1ccc(Cn2nnc(C(=O)Nc3ccc(OC)cc3OC)c2N)cc1
Structure:
Search PDB for entries with ligand similarity: