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Target
Neuropeptides B/W receptor type 1
Ligand
BDBM62079
Substrate
n/a
Meas. Tech.
Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7).
IC50
22456±n/a nM
Citation
 PubChem, PC Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7). PubChem Bioassay (2010)[AID] 
Target
Name:
Neuropeptides B/W receptor type 1
Synonyms:
GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36111.82
Organism:
Homo sapiens (Human)
Description:
gi_119607128
Residue:
328
Sequence:
MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
  
Inhibitor
Name:
BDBM62079
Synonyms:
(4-Chloro-phenyl)-[4-ethyl-5-(2-piperidin-1-yl-ethylsulfanyl)-4H-[1,2,4]triazol-3-ylmethyl]-amine | (4-chlorophenyl)-[[4-ethyl-5-(2-piperidinoethylthio)-1,2,4-triazol-3-yl]methyl]amine | 4-chloranyl-N-[[4-ethyl-5-(2-piperidin-1-ylethylsulfanyl)-1,2,4-triazol-3-yl]methyl]aniline | 4-chloro-N-[[4-ethyl-5-(2-piperidin-1-ylethylsulfanyl)-1,2,4-triazol-3-yl]methyl]aniline | 4-chloro-N-[[4-ethyl-5-[2-(1-piperidinyl)ethylthio]-1,2,4-triazol-3-yl]methyl]aniline | MLS000526884 | SMR000117358 | cid_1082177
Type:
Small organic molecule
Emp. Form.:
C18H26ClN5S
Mol. Mass.:
379.951
SMILES:
CCn1c(CNc2ccc(Cl)cc2)nnc1SCCN1CCCCC1
Structure:
Search PDB for entries with ligand similarity: