Target
Neuropeptides B/W receptor type 1
Ligand
BDBM62087
Substrate
n/a
Meas. Tech.
Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7).
IC50
35287±n/a nM
Citation
 PubChem, PC Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7). PubChem Bioassay (2010)[AID] 
Target
Name:
Neuropeptides B/W receptor type 1
Synonyms:
GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36111.82
Organism:
Homo sapiens (Human)
Description:
gi_119607128
Residue:
328
Sequence:
MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
  
Inhibitor
Name:
BDBM62087
Synonyms:
2-[[[2-[[2-(benzyloxycarbonylamino)acetyl]amino]-5-methyl-phenyl]-phenyl-methyl]amino]acetic acid methyl ester | 2-[[[5-methyl-2-[[1-oxo-2-(phenylmethoxycarbonylamino)ethyl]amino]phenyl]-phenylmethyl]amino]acetic acid methyl ester | MLS000324743 | SMR000163715 | cid_3527724 | methyl 2-[[[5-methyl-2-[2-(phenylmethoxycarbonylamino)ethanoylamino]phenyl]-phenyl-methyl]amino]ethanoate | methyl 2-[[[5-methyl-2-[[2-(phenylmethoxycarbonylamino)acetyl]amino]phenyl]-phenylmethyl]amino]acetate | methyl {[{2-[({[(benzyloxy)carbonyl]amino}acetyl)amino]-5-methylphenyl}(phenyl)methyl]amino}acetate
Type:
Small organic molecule
Emp. Form.:
C27H29N3O5
Mol. Mass.:
475.5363
SMILES:
COC(=O)CNC(c1ccccc1)c1cc(C)ccc1NC(=O)CNC(=O)OCc1ccccc1
Structure:
Search PDB for entries with ligand similarity: