Target
Neuropeptides B/W receptor type 1
Ligand
BDBM62090
Substrate
n/a
Meas. Tech.
Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7).
IC50
25607±n/a nM
Citation
 PubChem, PC Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7). PubChem Bioassay (2010)[AID] 
Target
Name:
Neuropeptides B/W receptor type 1
Synonyms:
GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36111.82
Organism:
Homo sapiens (Human)
Description:
gi_119607128
Residue:
328
Sequence:
MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
  
Inhibitor
Name:
BDBM62090
Synonyms:
(3-methyl-4-nitro-phenyl)-[4-(phenylmethyl)piperidin-1-yl]methanone | (3-methyl-4-nitrophenyl)-[4-(phenylmethyl)-1-piperidinyl]methanone | (4-benzylpiperidin-1-yl)-(3-methyl-4-nitrophenyl)methanone | (4-benzylpiperidino)-(3-methyl-4-nitro-phenyl)methanone | 4-benzyl-1-(3-methyl-4-nitrobenzoyl)piperidine | MLS000579123 | SMR000186712 | cid_786990
Type:
Small organic molecule
Emp. Form.:
C20H22N2O3
Mol. Mass.:
338.4003
SMILES:
Cc1cc(ccc1[N+]([O-])=O)C(=O)N1CCC(Cc2ccccc2)CC1
Structure:
Search PDB for entries with ligand similarity: