Reaction Details Report a problem with these data
Target
Neuropeptides B/W receptor type 1
Ligand
BDBM62094
Substrate
n/a
Meas. Tech.
Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7).
IC50
28013±n/a nM
Citation
 PubChem, PC Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7). PubChem Bioassay (2010)[AID] 
Target
Name:
Neuropeptides B/W receptor type 1
Synonyms:
GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36111.82
Organism:
Homo sapiens (Human)
Description:
gi_119607128
Residue:
328
Sequence:
MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
  
Inhibitor
Name:
BDBM62094
Synonyms:
Benzoic acid 4-{[2-(2,6-dimethyl-4-nitro-phenoxy)-acetyl]-hydrazonomethyl}-phenyl ester | MLS000567003 | SMR000174230 | [4-[[2-(2,6-dimethyl-4-nitro-phenoxy)ethanoylhydrazinylidene]methyl]phenyl] benzoate | [4-[[[2-(2,6-dimethyl-4-nitrophenoxy)acetyl]hydrazinylidene]methyl]phenyl] benzoate | benzoic acid [4-[[[2-(2,6-dimethyl-4-nitro-phenoxy)acetyl]hydrazono]methyl]phenyl] ester | benzoic acid [4-[[[2-(2,6-dimethyl-4-nitrophenoxy)-1-oxoethyl]hydrazinylidene]methyl]phenyl] ester | cid_1138091
Type:
Small organic molecule
Emp. Form.:
C24H21N3O6
Mol. Mass.:
447.44
SMILES:
Cc1cc(cc(C)c1OCC(=O)NN=Cc1ccc(OC(=O)c2ccccc2)cc1)[N+]([O-])=O
Structure:
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