Target
Neuropeptides B/W receptor type 1
Ligand
BDBM62097
Substrate
n/a
Meas. Tech.
Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7).
IC50
43807±n/a nM
Citation
 PubChem, PC Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7). PubChem Bioassay (2010)[AID] 
Target
Name:
Neuropeptides B/W receptor type 1
Synonyms:
GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36111.82
Organism:
Homo sapiens (Human)
Description:
gi_119607128
Residue:
328
Sequence:
MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
  
Inhibitor
Name:
BDBM62097
Synonyms:
MLS000584457 | N-cyclooctyl-3-keto-2-(2-thenyl)isoindoline-1-carboxamide | N-cyclooctyl-3-oxidanylidene-2-(thiophen-2-ylmethyl)-1H-isoindole-1-carboxamide | N-cyclooctyl-3-oxo-2-(thien-2-ylmethyl)isoindoline-1-carboxamide | N-cyclooctyl-3-oxo-2-(thiophen-2-ylmethyl)-1H-isoindole-1-carboxamide | SMR000207043 | cid_4439874
Type:
Small organic molecule
Emp. Form.:
C22H26N2O2S
Mol. Mass.:
382.519
SMILES:
O=C(NC1CCCCCCC1)C1N(Cc2cccs2)C(=O)c2ccccc12
Structure:
Search PDB for entries with ligand similarity: