Reaction Details Report a problem with these data
Target
Neuropeptides B/W receptor type 1
Ligand
BDBM62109
Substrate
n/a
Meas. Tech.
Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7).
IC50
21979±n/a nM
Citation
 PubChem, PC Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7). PubChem Bioassay (2010)[AID] 
Target
Name:
Neuropeptides B/W receptor type 1
Synonyms:
GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36111.82
Organism:
Homo sapiens (Human)
Description:
gi_119607128
Residue:
328
Sequence:
MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
  
Inhibitor
Name:
BDBM62109
Synonyms:
MLS000733675 | SMR000317538 | [1-(2,4-dimethyl-6-pyrazol-1-yl-benzyl)-3-m-anisyl-3-piperidyl]methanol | [1-[(2,4-dimethyl-6-pyrazol-1-yl-phenyl)methyl]-3-[(3-methoxyphenyl)methyl]piperidin-3-yl]methanol | [1-[(2,4-dimethyl-6-pyrazol-1-ylphenyl)methyl]-3-[(3-methoxyphenyl)methyl]piperidin-3-yl]methanol | [1-[2,4-dimethyl-6-(1H-pyrazol-1-yl)benzyl]-3-(3-methoxybenzyl)piperidin-3-yl]methanol | [1-[[2,4-dimethyl-6-(1-pyrazolyl)phenyl]methyl]-3-[(3-methoxyphenyl)methyl]-3-piperidinyl]methanol | cid_16191617
Type:
Small organic molecule
Emp. Form.:
C26H33N3O2
Mol. Mass.:
419.5591
SMILES:
COc1cccc(CC2(CO)CCCN(Cc3c(C)cc(C)cc3-n3cccn3)C2)c1
Structure:
Search PDB for entries with ligand similarity: