Reaction Details Report a problem with these data
Target
Neuropeptides B/W receptor type 1
Ligand
BDBM62121
Substrate
n/a
Meas. Tech.
Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7).
IC50
14602±n/a nM
Citation
 PubChem, PC Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7). PubChem Bioassay (2010)[AID] 
Target
Name:
Neuropeptides B/W receptor type 1
Synonyms:
GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36111.82
Organism:
Homo sapiens (Human)
Description:
gi_119607128
Residue:
328
Sequence:
MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
  
Inhibitor
Name:
BDBM62121
Synonyms:
MLS001007361 | N-(2-ethoxyphenyl)-2-phenyl-2-[(1-piperidin-1-ylcyclohexyl)methylamino]acetamide;oxalic acid | N-(2-ethoxyphenyl)-2-phenyl-2-[[1-(1-piperidinyl)cyclohexyl]methylamino]acetamide;oxalic acid | N-o-phenetyl-2-phenyl-2-[(1-piperidinocyclohexyl)methylamino]acetamide;oxalic acid | SMR000384549 | cid_16196062 | ethanedioic acid;N-(2-ethoxyphenyl)-2-phenyl-2-[(1-piperidin-1-ylcyclohexyl)methylamino]ethanamide
Type:
Small organic molecule
Emp. Form.:
C28H39N3O2
Mol. Mass.:
449.6282
SMILES:
CCOc1ccccc1NC(=O)C(NCC1(CCCCC1)N1CCCCC1)c1ccccc1
Structure:
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