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Target
Neuropeptides B/W receptor type 1
Ligand
BDBM62124
Substrate
n/a
Meas. Tech.
Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7).
IC50
14602±n/a nM
Citation
 PubChem, PC Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7). PubChem Bioassay (2010)[AID] 
Target
Name:
Neuropeptides B/W receptor type 1
Synonyms:
GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36111.82
Organism:
Homo sapiens (Human)
Description:
gi_119607128
Residue:
328
Sequence:
MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
  
Inhibitor
Name:
BDBM62124
Synonyms:
(4Z)-4-[[[4-(4-fluorophenyl)-2-methylimino-1,3-thiazol-3-yl]amino]methylidene]-2-hydroxycyclohexa-2,5-dien-1-one | (4Z)-4-[[[4-(4-fluorophenyl)-2-methylimino-1,3-thiazol-3-yl]amino]methylidene]-2-oxidanyl-cyclohexa-2,5-dien-1-one | (4Z)-4-[[[4-(4-fluorophenyl)-2-methylimino-3-thiazolyl]amino]methylidene]-2-hydroxy-1-cyclohexa-2,5-dienone | (4Z)-4-[[[4-(4-fluorophenyl)-2-methylimino-4-thiazolin-3-yl]amino]methylene]-2-hydroxy-cyclohexa-2,5-dien-1-one | MLS000775646 | SMR000370534 | cid_16196423
Type:
Small organic molecule
Emp. Form.:
C17H14FN3O2S
Mol. Mass.:
343.375
SMILES:
CN=c1scc(-c2ccc(F)cc2)n1N=Cc1ccc(O)c(O)c1 |w:14.15,1.0|
Structure:
Search PDB for entries with ligand similarity: