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Target
Neuropeptides B/W receptor type 1
Ligand
BDBM62150
Substrate
n/a
Meas. Tech.
Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7).
IC50
43807±n/a nM
Citation
 PubChem, PC Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7). PubChem Bioassay (2010)[AID] 
Target
Name:
Neuropeptides B/W receptor type 1
Synonyms:
GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36111.82
Organism:
Homo sapiens (Human)
Description:
gi_119607128
Residue:
328
Sequence:
MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
  
Inhibitor
Name:
BDBM62150
Synonyms:
1-[3-(4-fluorophenyl)-4-isoxazolo[5,4-d]pyrimidinyl]-N-(2-methylphenyl)-3-piperidinecarboxamide | 1-[3-(4-fluorophenyl)-[1,2]oxazolo[5,4-d]pyrimidin-4-yl]-N-(2-methylphenyl)piperidine-3-carboxamide | 1-[3-(4-fluorophenyl)isoxazolo[5,4-d]pyrimidin-4-yl]-N-(o-tolyl)nipecotamide | MLS001116557 | SMR000630078 | cid_20924828
Type:
Small organic molecule
Emp. Form.:
C24H22FN5O2
Mol. Mass.:
431.4622
SMILES:
Cc1ccccc1NC(=O)C1CCCN(C1)c1ncnc2onc(-c3ccc(F)cc3)c12
Structure:
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