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Target
Neuropeptides B/W receptor type 1
Ligand
BDBM62155
Substrate
n/a
Meas. Tech.
Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7).
IC50
43807±n/a nM
Citation
 PubChem, PC Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7). PubChem Bioassay (2010)[AID] 
Target
Name:
Neuropeptides B/W receptor type 1
Synonyms:
GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36111.82
Organism:
Homo sapiens (Human)
Description:
gi_119607128
Residue:
328
Sequence:
MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
  
Inhibitor
Name:
BDBM62155
Synonyms:
Furan-2-carboxylic acid [cyclohexylcarbamoyl-(3,4,5-trimethoxy-phenyl)-methyl]-(2-methoxy-phenyl)-amide | MLS001220116 | N-[2-(cyclohexylamino)-2-keto-1-(3,4,5-trimethoxyphenyl)ethyl]-N-(2-methoxyphenyl)-2-furamide | N-[2-(cyclohexylamino)-2-oxidanylidene-1-(3,4,5-trimethoxyphenyl)ethyl]-N-(2-methoxyphenyl)furan-2-carboxamide | N-[2-(cyclohexylamino)-2-oxo-1-(3,4,5-trimethoxyphenyl)ethyl]-N-(2-methoxyphenyl)-2-furancarboxamide | N-[2-(cyclohexylamino)-2-oxo-1-(3,4,5-trimethoxyphenyl)ethyl]-N-(2-methoxyphenyl)furan-2-carboxamide | SMR000600212 | cid_3191330
Type:
Small organic molecule
Emp. Form.:
C29H34N2O7
Mol. Mass.:
522.5895
SMILES:
COc1cc(cc(OC)c1OC)C(N(C(=O)c1ccco1)c1ccccc1OC)C(=O)NC1CCCCC1
Structure:
Search PDB for entries with ligand similarity: