Target
Kappa-type opioid receptor
Ligand
BDBM62196
Substrate
n/a
Meas. Tech.
SAR analysis of small molecule antagonists of the kappa opioid receptor via a luminescent beta-arrestin assay
IC50
10000±n/a nM
Citation
 PubChem, PC SAR analysis of small molecule antagonists of the kappa opioid receptor via a luminescent beta-arrestin assay PubChem Bioassay (2010)[AID] 
Target
Name:
Kappa-type opioid receptor
Synonyms:
K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42648.76
Organism:
Homo sapiens (Human)
Description:
P41145
Residue:
380
Sequence:
MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRVRNTVQDPAYLRDIDGMNKPV
  
Inhibitor
Name:
BDBM62196
Synonyms:
(phenylmethyl) N-[1-[(4-bromophenyl)carbamothioylamino]-2,2,2-tris(chloranyl)ethyl]carbamate | MLS-0425697.0001 | N-[1-[(4-bromophenyl)thiocarbamoylamino]-2,2,2-trichloro-ethyl]carbamic acid benzyl ester | N-[1-[[(4-bromoanilino)-sulfanylidenemethyl]amino]-2,2,2-trichloroethyl]carbamic acid (phenylmethyl) ester | benzyl N-[1-[(4-bromophenyl)carbamothioylamino]-2,2,2-trichloroethyl]carbamate | cid_3091268
Type:
Small organic molecule
Emp. Form.:
C17H15BrCl3N3O2S
Mol. Mass.:
511.648
SMILES:
ClC(Cl)(Cl)C(NC(=O)OCc1ccccc1)NC(=S)Nc1ccc(Br)cc1
Structure:
Search PDB for entries with ligand similarity: