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Target
Regulator of G-protein signaling 4
Ligand
BDBM62220
Substrate
n/a
Meas. Tech.
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao for SAR compounds
EC50
30000±n/a nM
Citation
 PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao for SAR compounds PubChem Bioassay (2010)[AID] 
Target
Name:
Regulator of G-protein signaling 4
Synonyms:
RGP4 | RGS4 | RGS4_HUMAN | Regulator of G-protein signaling 4 (RGS4)
Type:
Enzyme
Mol. Mass.:
23263.51
Organism:
Homo sapiens (Human)
Description:
P49798
Residue:
205
Sequence:
MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSCEHNSSHNKKDKVVICQRVSQEEVKKWAESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFISVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLVNPSSCGAEKQKGAKSSADCASLVPQCA
  
Inhibitor
Name:
BDBM62220
Synonyms:
2,4-dimethyl-6-[2-[3-methyl-4-(3-methylphenyl)-1-piperazinyl]-2-oxoethyl]-7,8-dihydro-1,6-naphthyridin-5-one | 2,4-dimethyl-6-[2-[3-methyl-4-(3-methylphenyl)piperazin-1-yl]-2-oxidanylidene-ethyl]-7,8-dihydro-1,6-naphthyridin-5-one | 2,4-dimethyl-6-[2-[3-methyl-4-(3-methylphenyl)piperazin-1-yl]-2-oxoethyl]-7,8-dihydro-1,6-naphthyridin-5-one | 6-[2-keto-2-[3-methyl-4-(m-tolyl)piperazino]ethyl]-2,4-dimethyl-7,8-dihydro-1,6-naphthyridin-5-one | KUC103675N | cid_44473131
Type:
Small organic molecule
Emp. Form.:
C24H30N4O2
Mol. Mass.:
406.5206
SMILES:
CC1CN(CCN1c1cccc(C)c1)C(=O)CN1CCc2nc(C)cc(C)c2C1=O
Structure:
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