Target
Regulator of G-protein signaling 16
Ligand
BDBM47747
Substrate
n/a
Meas. Tech.
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao for SAR Compounds
EC50
940±101.7 nM
Citation
 PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao for SAR Compounds PubChem Bioassay (2010)[AID] 
Target
Name:
Regulator of G-protein signaling 16
Synonyms:
RGS16 | RGS16_HUMAN | RGSR | Regulator of G-protein signaling 16 (RGS16) | regulator of G-protein signalling 16
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22748.87
Organism:
Homo sapiens (Human)
Description:
gi_156416009
Residue:
202
Sequence:
MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVLGWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEEFICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDLAAQASAASATLSSCSLDEPSHT
  
Inhibitor
Name:
BDBM47747
Synonyms:
4-[(E)-[3-[3-(diethylsulfamoyl)phenyl]-5-thioxo-1H-1,2,4-triazol-4-yl]iminomethyl]benzoic acid methyl ester | 4-[[3-[3-(diethylsulfamoyl)phenyl]-5-sulfanylidene-1H-1,2,4-triazol-4-yl]iminomethyl]benzoic acid methyl ester | 4-[[3-[3-(diethylsulfamoyl)phenyl]-5-thioxo-1H-1,2,4-triazol-4-yl]iminomethyl]benzoic acid methyl ester | MLS000408811 | SMR000243078 | cid_2387418 | methyl 4-[[3-[3-(diethylsulfamoyl)phenyl]-5-sulfanylidene-1H-1,2,4-triazol-4-yl]iminomethyl]benzoate
Type:
Small organic molecule
Emp. Form.:
C21H23N5O4S2
Mol. Mass.:
473.568
SMILES:
CCN(CC)S(=O)(=O)c1cccc(c1)-c1n[nH]c(=S)n1N=Cc1ccc(cc1)C(=O)OC |w:20.21|
Structure:
Search PDB for entries with ligand similarity: