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Target
Sphingosine 1-phosphate receptor 4
Ligand
BDBM47469
Substrate
n/a
Meas. Tech.
Late stage fluorescence dose response cell-based screening assay for antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)
IC50
4548±n/a nM
Citation
 PubChem, PC Late stage fluorescence dose response cell-based screening assay for antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4) PubChem Bioassay (2010)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 4
Synonyms:
EDG6 | Endothelial differentiation G-protein coupled receptor 6 | S1P receptor 4 | S1P receptor Edg-6 | S1P4 | S1PR4 | S1PR4_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-6 | Sphingosine-1-phosphate receptor 4 | sphingosine-1-phosphate 4 S1P4
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
41647.39
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
384
Sequence:
MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLVVLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFLREGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLPLLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRPAARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNSAVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDSFRGSRSLSFRMREPLSSISSVRSI
  
Inhibitor
Name:
BDBM47469
Synonyms:
2-keto-4-phenylimino-N-styrylidene-but-3-enamide | 2-oxidanylidene-N-(2-phenylethenylidene)-4-phenylimino-but-3-enamide | 2-oxo-N-(2-phenylethenylidene)-4-phenylimino-3-butenamide | 2-oxo-N-(2-phenylethenylidene)-4-phenyliminobut-3-enamide | MLS000737077 | SMR000394031 | cid_238775
Type:
Small organic molecule
Emp. Form.:
C18H12N2O2
Mol. Mass.:
288.3001
SMILES:
O=C(C=C=Nc1ccccc1)C(=O)N=C=Cc1ccccc1
Structure:
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