Reaction Details Report a problem with these data
Target
G-protein coupled receptor 35
Ligand
BDBM61037
Substrate
n/a
Meas. Tech.
SAR analysis of Antagonists of the GPR35 Receptor using an Image-Based Assay
IC50
32000±n/a nM
Citation
 PubChem, PC SAR analysis of Antagonists of the GPR35 Receptor using an Image-Based Assay PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM61037
Synonyms:
2-(1,3-benzothiazol-2-ylsulfanyl)-1-[2-(trifluoromethyl)phenothiazin-10-yl]ethanone | 2-(1,3-benzothiazol-2-ylthio)-1-[2-(trifluoromethyl)-10-phenothiazinyl]ethanone | 2-(1,3-benzothiazol-2-ylthio)-1-[2-(trifluoromethyl)phenothiazin-10-yl]ethanone | 2-(Benzothiazol-2-ylsulfanyl)-1-(2-trifluoromethyl-phenothiazin-10-yl)-ethanone | MLS000549754 | SMR000176186 | cid_1724914
Type:
Small organic molecule
Emp. Form.:
C22H13F3N2OS3
Mol. Mass.:
474.542
SMILES:
FC(F)(F)c1ccc2Sc3ccccc3N(C(=O)CSc3nc4ccccc4s3)c2c1
Structure:
Search PDB for entries with ligand similarity: