Reaction Details Report a problem with these data
Target
Mu-type opioid receptor
Ligand
BDBM62084
Substrate
n/a
Meas. Tech.
SAR Analysis of Agonists of the MOR Receptor using an Image-Based Assay
EC50
>32000±n/a nM
Citation
 PubChem, PC SAR Analysis of Agonists of the MOR Receptor using an Image-Based Assay PubChem Bioassay (2010)[AID] 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM62084
Synonyms:
MLS000519748 | N-[1-(cyclopentylcarbamoyl)cyclohexyl]-N-(2-furfuryl)pyrazinamide | N-[1-(cyclopentylcarbamoyl)cyclohexyl]-N-(furan-2-ylmethyl)pyrazine-2-carboxamide | N-[1-[(cyclopentylamino)-oxomethyl]cyclohexyl]-N-(2-furanylmethyl)-2-pyrazinecarboxamide | SMR000130166 | cid_4579040
Type:
Small organic molecule
Emp. Form.:
C22H28N4O3
Mol. Mass.:
396.4827
SMILES:
O=C(NC1CCCC1)C1(CCCCC1)N(Cc1ccco1)C(=O)c1cnccn1
Structure:
Search PDB for entries with ligand similarity: