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Target
Delta-type opioid receptor
Ligand
BDBM54811
Substrate
n/a
Meas. Tech.
HTS Image-Based Screen for Antagonists of the DOR Receptor
IC50
4697±n/a nM
Citation
 PubChem, PC HTS Image-Based Screen for Antagonists of the DOR Receptor PubChem Bioassay (2010)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM54811
Synonyms:
7-chloranyl-3-phenyl-[1,3]thiazolo[4,5-d]pyrimidine-2-thione | 7-chloro-3-phenyl-2-thiazolo[4,5-d]pyrimidinethione | 7-chloro-3-phenyl-[1,3]thiazolo[4,5-d]pyrimidine-2-thione | 7-chloro-3-phenyl-thiazolo[4,5-d]pyrimidine-2-thione | 7-chloro-3-phenyl[1,3]thiazolo[4,5-d]pyrimidine-2(3H)-thione | MLS000727642 | SMR000306339 | cid_373692
Type:
Small organic molecule
Emp. Form.:
C11H6ClN3S2
Mol. Mass.:
279.768
SMILES:
Clc1ncnc2n(-c3ccccc3)c(=S)sc12
Structure:
Search PDB for entries with ligand similarity: