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Target
Delta-type opioid receptor
Ligand
BDBM54834
Substrate
n/a
Meas. Tech.
HTS Image-Based Screen for Antagonists of the DOR Receptor
IC50
24397±n/a nM
Citation
 PubChem, PC HTS Image-Based Screen for Antagonists of the DOR Receptor PubChem Bioassay (2010)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM54834
Synonyms:
(3-asaryl-1-methyl-propyl)-(3,3-diphenylpropyl)amine;hydrochloride | MLS001173618 | N-(3,3-diphenylpropyl)-4-(2,4,5-trimethoxyphenyl)-2-butanamine;hydrochloride | N-(3,3-diphenylpropyl)-4-(2,4,5-trimethoxyphenyl)butan-2-amine;hydrochloride | SMR000538752 | cid_24747640
Type:
Small organic molecule
Emp. Form.:
C28H35NO3
Mol. Mass.:
433.5824
SMILES:
COc1cc(OC)c(OC)cc1CCC(C)NCCC(c1ccccc1)c1ccccc1
Structure:
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