Target
Delta-type opioid receptor
Ligand
BDBM62173
Substrate
n/a
Meas. Tech.
SAR Analysis of Antagonists of the DOR Receptor using an Image-Based Assay
IC50
32000±n/a nM
Citation
 PubChem, PC SAR Analysis of Antagonists of the DOR Receptor using an Image-Based Assay PubChem Bioassay (2010)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM62173
Synonyms:
2-(3-keto-1,4-benzoxazin-4-yl)-N-p-anisyl-N-(2-pyridylmethyl)acetamide | MLS-0043215.0001 | N-[(4-methoxyphenyl)methyl]-2-(3-oxidanylidene-1,4-benzoxazin-4-yl)-N-(pyridin-2-ylmethyl)ethanamide | N-[(4-methoxyphenyl)methyl]-2-(3-oxo-1,4-benzoxazin-4-yl)-N-(2-pyridinylmethyl)acetamide | N-[(4-methoxyphenyl)methyl]-2-(3-oxo-1,4-benzoxazin-4-yl)-N-(pyridin-2-ylmethyl)acetamide | cid_653720
Type:
Small organic molecule
Emp. Form.:
C24H23N3O4
Mol. Mass.:
417.4571
SMILES:
COc1ccc(CN(Cc2ccccn2)C(=O)CN2C(=O)COc3ccccc23)cc1
Structure:
Search PDB for entries with ligand similarity: