Target
Delta-type opioid receptor
Ligand
BDBM62190
Substrate
n/a
Meas. Tech.
SAR Analysis of Antagonists of the DOR Receptor using an Image-Based Assay
IC50
32000±n/a nM
Citation
 PubChem, PC SAR Analysis of Antagonists of the DOR Receptor using an Image-Based Assay PubChem Bioassay (2010)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM62190
Synonyms:
4-[[(4-acetylphenyl)sulfonylamino]methyl]-N-[2-(3-fluoroanilino)-2-keto-ethyl]-N-methyl-benzamide | 4-[[(4-acetylphenyl)sulfonylamino]methyl]-N-[2-(3-fluoroanilino)-2-oxoethyl]-N-methylbenzamide | 4-[[(4-ethanoylphenyl)sulfonylamino]methyl]-N-[2-[(3-fluorophenyl)amino]-2-oxidanylidene-ethyl]-N-methyl-benzamide | MLS-0332830.0001 | cid_16295215
Type:
Small organic molecule
Emp. Form.:
C25H24FN3O5S
Mol. Mass.:
497.539
SMILES:
CN(CC(=O)Nc1cccc(F)c1)C(=O)c1ccc(CNS(=O)(=O)c2ccc(cc2)C(C)=O)cc1
Structure:
Search PDB for entries with ligand similarity: