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Target
Kappa-type opioid receptor
Ligand
BDBM46582
Substrate
n/a
Meas. Tech.
SAR analysis of Agonists of the Kappa Opioid Receptor (KOR) using an Image-Based Assay
EC50
>32000±n/a nM
Citation
 PubChem, PC SAR analysis of Agonists of the Kappa Opioid Receptor (KOR) using an Image-Based Assay PubChem Bioassay (2010)[AID] 
Target
Name:
Kappa-type opioid receptor
Synonyms:
K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42648.76
Organism:
Homo sapiens (Human)
Description:
P41145
Residue:
380
Sequence:
MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRVRNTVQDPAYLRDIDGMNKPV
  
Inhibitor
Name:
BDBM46582
Synonyms:
(4Z)-4-[[(7-chloro-4-quinolinyl)hydrazo]methylidene]-2-hydroxy-1-cyclohexa-2,5-dienone | (4Z)-4-[[2-(7-chloranylquinolin-4-yl)hydrazinyl]methylidene]-2-oxidanyl-cyclohexa-2,5-dien-1-one | (4Z)-4-[[2-(7-chloroquinolin-4-yl)hydrazinyl]methylidene]-2-hydroxycyclohexa-2,5-dien-1-one | (4Z)-4-[[N'-(7-chloro-4-quinolyl)hydrazino]methylene]-2-hydroxy-cyclohexa-2,5-dien-1-one | MLS000760794 | SMR000370908 | cid_6524677
Type:
Small organic molecule
Emp. Form.:
C16H12ClN3O2
Mol. Mass.:
313.738
SMILES:
Oc1ccc(CN=Nc2ccnc3cc(Cl)ccc23)cc1O |w:7.7|
Structure:
Search PDB for entries with ligand similarity: