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Target
Kappa-type opioid receptor
Ligand
BDBM54788
Substrate
n/a
Meas. Tech.
SAR analysis of Agonists of the Kappa Opioid Receptor (KOR) using an Image-Based Assay
EC50
4930±n/a nM
Citation
 PubChem, PC SAR analysis of Agonists of the Kappa Opioid Receptor (KOR) using an Image-Based Assay PubChem Bioassay (2010)[AID] 
Target
Name:
Kappa-type opioid receptor
Synonyms:
K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42648.76
Organism:
Homo sapiens (Human)
Description:
P41145
Residue:
380
Sequence:
MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRVRNTVQDPAYLRDIDGMNKPV
  
Inhibitor
Name:
BDBM54788
Synonyms:
MLS000778656 | N-butyl-N-[(2-keto-6-methyl-1H-quinolin-3-yl)methyl]picolinamide | N-butyl-N-[(6-methyl-2-oxidanylidene-1H-quinolin-3-yl)methyl]pyridine-2-carboxamide | N-butyl-N-[(6-methyl-2-oxo-1H-quinolin-3-yl)methyl]-2-pyridinecarboxamide | N-butyl-N-[(6-methyl-2-oxo-1H-quinolin-3-yl)methyl]pyridine-2-carboxamide | Pyridine-2-carboxylic acid butyl-(2-hydroxy-6-methyl-quinolin-3-ylmethyl)-amide | SMR000415450 | cid_1636023
Type:
Small organic molecule
Emp. Form.:
C21H23N3O2
Mol. Mass.:
349.4262
SMILES:
CCCCN(Cc1cc2cc(C)ccc2[nH]c1=O)C(=O)c1ccccn1
Structure:
Search PDB for entries with ligand similarity: