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Target
Delta-type opioid receptor
Ligand
BDBM46582
Substrate
n/a
Meas. Tech.
SAR Analysis of Agonists of the DOR Receptor using an Image-Based Assay
EC50
>32000±n/a nM
Citation
 PubChem, PC SAR Analysis of Agonists of the DOR Receptor using an Image-Based Assay PubChem Bioassay (2010)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM46582
Synonyms:
(4Z)-4-[[(7-chloro-4-quinolinyl)hydrazo]methylidene]-2-hydroxy-1-cyclohexa-2,5-dienone | (4Z)-4-[[2-(7-chloranylquinolin-4-yl)hydrazinyl]methylidene]-2-oxidanyl-cyclohexa-2,5-dien-1-one | (4Z)-4-[[2-(7-chloroquinolin-4-yl)hydrazinyl]methylidene]-2-hydroxycyclohexa-2,5-dien-1-one | (4Z)-4-[[N'-(7-chloro-4-quinolyl)hydrazino]methylene]-2-hydroxy-cyclohexa-2,5-dien-1-one | MLS000760794 | SMR000370908 | cid_6524677
Type:
Small organic molecule
Emp. Form.:
C16H12ClN3O2
Mol. Mass.:
313.738
SMILES:
Oc1ccc(CN=Nc2ccnc3cc(Cl)ccc23)cc1O |w:7.7|
Structure:
Search PDB for entries with ligand similarity: