Target
Delta-type opioid receptor
Ligand
BDBM62174
Substrate
n/a
Meas. Tech.
SAR Analysis of Agonists of the DOR Receptor using an Image-Based Assay
EC50
>32000±n/a nM
Citation
 PubChem, PC SAR Analysis of Agonists of the DOR Receptor using an Image-Based Assay PubChem Bioassay (2010)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM62174
Synonyms:
MLS-0015756.0001 | N-cyclohexyl-N-[(2-keto-1H-quinolin-3-yl)methyl]picolinamide | N-cyclohexyl-N-[(2-oxidanylidene-1H-quinolin-3-yl)methyl]pyridine-2-carboxamide | N-cyclohexyl-N-[(2-oxo-1H-quinolin-3-yl)methyl]-2-pyridinecarboxamide | N-cyclohexyl-N-[(2-oxo-1H-quinolin-3-yl)methyl]pyridine-2-carboxamide | cid_665086
Type:
Small organic molecule
Emp. Form.:
C22H23N3O2
Mol. Mass.:
361.4369
SMILES:
O=C(N(Cc1cc2ccccc2[nH]c1=O)C1CCCCC1)c1ccccn1
Structure:
Search PDB for entries with ligand similarity: