Target
Delta-type opioid receptor
Ligand
BDBM62177
Substrate
n/a
Meas. Tech.
SAR Analysis of Agonists of the DOR Receptor using an Image-Based Assay
EC50
>32000±n/a nM
Citation
 PubChem, PC SAR Analysis of Agonists of the DOR Receptor using an Image-Based Assay PubChem Bioassay (2010)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM62177
Synonyms:
MLS-0391854.0001 | N-[(2-keto-6-methyl-1H-quinolin-3-yl)methyl]-N-propyl-picolinamide | N-[(6-methyl-2-oxidanylidene-1H-quinolin-3-yl)methyl]-N-propyl-pyridine-2-carboxamide | N-[(6-methyl-2-oxo-1H-quinolin-3-yl)methyl]-N-propyl-2-pyridinecarboxamide | N-[(6-methyl-2-oxo-1H-quinolin-3-yl)methyl]-N-propylpyridine-2-carboxamide | cid_3440378
Type:
Small organic molecule
Emp. Form.:
C20H21N3O2
Mol. Mass.:
335.3996
SMILES:
CCCN(Cc1cc2cc(C)ccc2[nH]c1=O)C(=O)c1ccccn1
Structure:
Search PDB for entries with ligand similarity: