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Target
Trans-activator protein BZLF1
Ligand
BDBM62445
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of EBNA-1: fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of the Epstein-Barr virus-encoded protein, ZTA
IC50
111248±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of EBNA-1: fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of the Epstein-Barr virus-encoded protein, ZTA PubChem Bioassay (2010)[AID] 
Target
Name:
Trans-activator protein BZLF1
Synonyms:
BZLF1 | BZLF1_EBVB9 | PPP5C protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
26856.37
Organism:
Human herpesvirus 4
Description:
gi_82503229
Residue:
245
Sequence:
MMDPNSTSEDVKFTPDPYQVPFVQAFDQATRVYQDLGGPSQAPLPCVLWPVLPEPLPQGQLTAYHVSTAPTGSWFSAPQPAPENAYQAYAAPQLFPVSDITQNQQTNQAGGEAPQPGDNSTVQTAAAVVFACPGANQGQQLADIGVPQPAPVAAPARRTRKPQQPESLEECDSELEIKRYKNRVASRKCRAKFKQLLQHYREVAAAKSSENDRLRLLLKQMCPSLDVDSIIPRTPDVLHEDLLNF
  
Inhibitor
Name:
BDBM62445
Synonyms:
MLS000553586 | N-[4-[2-(4-hydroxyphenyl)-1,3-bis(oxidanylidene)isoindol-5-yl]oxyphenyl]thiophene-2-carboxamide | N-[4-[2-(4-hydroxyphenyl)-1,3-diketo-isoindolin-5-yl]oxyphenyl]thiophene-2-carboxamide | N-[4-[2-(4-hydroxyphenyl)-1,3-dioxoisoindol-5-yl]oxyphenyl]thiophene-2-carboxamide | N-[4-[[2-(4-hydroxyphenyl)-1,3-dioxo-5-isoindolyl]oxy]phenyl]-2-thiophenecarboxamide | SMR000172103 | Thiophene-2-carboxylic acid {4-[2-(4-hydroxy-phenyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yloxy]-phenyl}-amide | cid_1107365
Type:
Small organic molecule
Emp. Form.:
C25H16N2O5S
Mol. Mass.:
456.47
SMILES:
Oc1ccc(cc1)N1C(=O)c2ccc(Oc3ccc(NC(=O)c4cccs4)cc3)cc2C1=O
Structure:
Search PDB for entries with ligand similarity: