Reaction Details Report a problem with these data
Target
Epstein-Barr nuclear antigen 1
Ligand
BDBM62431
Substrate
n/a
Meas. Tech.
Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the Epstein-Barr virus nuclear antigen 1 (EBNA-1)
IC50
11209±n/a nM
Citation
 PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the Epstein-Barr virus nuclear antigen 1 (EBNA-1) PubChem Bioassay (2010)[AID] 
Target
Name:
Epstein-Barr nuclear antigen 1
Synonyms:
EBNA-1 protein | EBNA1 | EBNA1_EBVB9 | Epstein-Barr virus protease (EBV Pr)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
56444.81
Organism:
Human herpesvirus 4
Description:
gi_23893623
Residue:
641
Sequence:
MSDEGPGTGPGNGLGEKGDTSGPEGSGGSGPQRRGGDNHGRGRGRGRGRGGGRPGAPGGSGSGPRHRDGVRRPQKRPSCIGCKGTHGGTGAGAGAGGAGAGGAGAGGGAGAGGGAGGAGGAGGAGAGGGAGAGGGAGGAGGAGAGGGAGAGGGAGGAGAGGGAGGAGGAGAGGGAGAGGGAGGAGAGGGAGGAGGAGAGGGAGAGGAGGAGGAGAGGAGAGGGAGGAGGAGAGGAGAGGAGAGGAGAGGAGGAGAGGAGGAGAGGAGGAGAGGGAGGAGAGGGAGGAGAGGAGGAGAGGAGGAGAGGAGGAGAGGGAGAGGAGAGGGGRGRGGSGGRGRGGSGGRGRGGSGGRRGRGRERARGGSRERARGRGRGRGEKRPRSPSSQSSSSGSPPRRPPPGRRPFFHPVGEADYFEYHQEGGPDGEPDVPPGAIEQGPADDPGEGPSTGPRGQGDGGRRKKGGWFGKHRGQGGSNPKFENIAEGLRALLARSHVERTTDEGTWVAGVFVYGGSKTSLYNLRRGTALAIPQCRLTPLSRLPFGMAPGPGPQPGPLRESIVCYFMVFLQTHIFAEVLKDAIKDLVMTKPAPTCNIRVTVCSFDDGVDLPPWFPPMVEGAAAEGDDGDDGDEGGDGDEGEEGQE
  
Inhibitor
Name:
BDBM62431
Synonyms:
(5E)-3-benzyl-5-[(1,3-dimethyl-2-oxobenzimidazol-5-yl)methylidene]imidazolidine-2,4-dione | (5E)-3-benzyl-5-[(2-keto-1,3-dimethyl-benzimidazol-5-yl)methylene]hydantoin | (5E)-5-[(1,3-dimethyl-2-oxidanylidene-benzimidazol-5-yl)methylidene]-3-(phenylmethyl)imidazolidine-2,4-dione | (5E)-5-[(1,3-dimethyl-2-oxo-5-benzimidazolyl)methylidene]-3-(phenylmethyl)imidazolidine-2,4-dione | 3-benzyl-5-[(1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)methylene]-2,4-imidazolidinedione | MLS000539109 | SMR000160447 | cid_1209501
Type:
Small organic molecule
Emp. Form.:
C20H18N4O3
Mol. Mass.:
362.3819
SMILES:
Cn1c2ccc(\C=C3\NC(=O)N(Cc4ccccc4)C3=O)cc2n(C)c1=O
Structure:
Search PDB for entries with ligand similarity: