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Target
Epstein-Barr nuclear antigen 1
Ligand
BDBM62484
Substrate
n/a
Meas. Tech.
Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the Epstein-Barr virus nuclear antigen 1 (EBNA-1)
IC50
12933±n/a nM
Citation
 PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the Epstein-Barr virus nuclear antigen 1 (EBNA-1) PubChem Bioassay (2010)[AID] 
Target
Name:
Epstein-Barr nuclear antigen 1
Synonyms:
EBNA-1 protein | EBNA1 | EBNA1_EBVB9 | Epstein-Barr virus protease (EBV Pr)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
56444.81
Organism:
Human herpesvirus 4
Description:
gi_23893623
Residue:
641
Sequence:
MSDEGPGTGPGNGLGEKGDTSGPEGSGGSGPQRRGGDNHGRGRGRGRGRGGGRPGAPGGSGSGPRHRDGVRRPQKRPSCIGCKGTHGGTGAGAGAGGAGAGGAGAGGGAGAGGGAGGAGGAGGAGAGGGAGAGGGAGGAGGAGAGGGAGAGGGAGGAGAGGGAGGAGGAGAGGGAGAGGGAGGAGAGGGAGGAGGAGAGGGAGAGGAGGAGGAGAGGAGAGGGAGGAGGAGAGGAGAGGAGAGGAGAGGAGGAGAGGAGGAGAGGAGGAGAGGGAGGAGAGGGAGGAGAGGAGGAGAGGAGGAGAGGAGGAGAGGGAGAGGAGAGGGGRGRGGSGGRGRGGSGGRGRGGSGGRRGRGRERARGGSRERARGRGRGRGEKRPRSPSSQSSSSGSPPRRPPPGRRPFFHPVGEADYFEYHQEGGPDGEPDVPPGAIEQGPADDPGEGPSTGPRGQGDGGRRKKGGWFGKHRGQGGSNPKFENIAEGLRALLARSHVERTTDEGTWVAGVFVYGGSKTSLYNLRRGTALAIPQCRLTPLSRLPFGMAPGPGPQPGPLRESIVCYFMVFLQTHIFAEVLKDAIKDLVMTKPAPTCNIRVTVCSFDDGVDLPPWFPPMVEGAAAEGDDGDDGDEGGDGDEGEEGQE
  
Inhibitor
Name:
BDBM62484
Synonyms:
9-(2,3-dimethoxyphenyl)-2-(3,4,5-trimethoxyphenyl)-5,6,7,9-tetrahydro-1H-[1,2,4]triazolo[5,1-b]quinazolin-8-one | 9-(2,3-dimethoxyphenyl)-2-(3,4,5-trimethoxyphenyl)-5,6,7,9-tetrahydro[1,2,4]triazolo[5,1-b]quinazolin-8(4H)-one | MLS000878792 | SMR000019605 | cid_5771350
Type:
Small organic molecule
Emp. Form.:
C26H28N4O6
Mol. Mass.:
492.5237
SMILES:
COc1cccc(C2C3C(=O)CCCC3=Nc3nc(nn23)-c2cc(OC)c(OC)c(OC)c2)c1OC |c:15|
Structure:
Search PDB for entries with ligand similarity: