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Target
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
Ligand
BDBM39886
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of PP5: fluorescence-based biochemical high throughput dose response assay for inhibitors of Protein Phosphatase 1 (PP1)
IC50
67047±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of PP5: fluorescence-based biochemical high throughput dose response assay for inhibitors of Protein Phosphatase 1 (PP1) PubChem Bioassay (2010)[AID] 
Target
Name:
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
Synonyms:
PP-1A | PP1A_HUMAN | PPP1A | PPP1CA | Serine/threonine protein phosphatase PP1-alpha catalytic subunit | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit | protein phosphatase 1, catalytic subunit, alpha isoform 3
Type:
PROTEIN
Mol. Mass.:
37510.66
Organism:
Homo sapiens (Human)
Description:
ChEMBL_197827
Residue:
330
Sequence:
MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK
  
Inhibitor
Name:
BDBM39886
Synonyms:
4b,9b-bis(oxidanyl)-7,8-dihydro-6H-indeno[1,2-b][1]benzofuran-9,10-dione | 4b,9b-dihydroxy-7,8-dihydro-6H-indeno[1,2-b][1]benzofuran-9,10-dione | 4b,9b-dihydroxy-7,8-dihydro-6H-indeno[1,2-b]benzofuran-9,10-dione | 4b,9b-dihydroxy-7,8-dihydro-6H-indeno[1,2-b]benzofuran-9,10-quinone | MLS000104338 | SMR000054273 | cid_2834991
Type:
Small organic molecule
Emp. Form.:
C15H12O5
Mol. Mass.:
272.2528
SMILES:
OC12OC3=C(C(=O)CCC3)C1(O)C(=O)c1ccccc21 |t:3|
Structure:
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