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Target
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
Ligand
BDBM41677
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of PP5: fluorescence-based biochemical high throughput dose response assay for inhibitors of Protein Phosphatase 1 (PP1)
IC50
67047±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of PP5: fluorescence-based biochemical high throughput dose response assay for inhibitors of Protein Phosphatase 1 (PP1) PubChem Bioassay (2010)[AID] 
Target
Name:
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
Synonyms:
PP-1A | PP1A_HUMAN | PPP1A | PPP1CA | Serine/threonine protein phosphatase PP1-alpha catalytic subunit | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit | protein phosphatase 1, catalytic subunit, alpha isoform 3
Type:
PROTEIN
Mol. Mass.:
37510.66
Organism:
Homo sapiens (Human)
Description:
ChEMBL_197827
Residue:
330
Sequence:
MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK
  
Inhibitor
Name:
BDBM41677
Synonyms:
2-Amino-1-benzo[1,3]dioxol-5-ylmethyl-1H-pyrrolo[2,3-b]quinoxaline-3-carboxylic acid isobutyl-amide | 2-amino-1-(1,3-benzodioxol-5-ylmethyl)-N-(2-methylpropyl)-3-pyrrolo[3,2-b]quinoxalinecarboxamide | 2-amino-1-(1,3-benzodioxol-5-ylmethyl)-N-(2-methylpropyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide | 2-amino-N-isobutyl-1-piperonyl-pyrrolo[3,2-b]quinoxaline-3-carboxamide | 2-azanyl-1-(1,3-benzodioxol-5-ylmethyl)-N-(2-methylpropyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide | MLS000556577 | SMR000147894 | cid_3800606
Type:
Small organic molecule
Emp. Form.:
C23H23N5O3
Mol. Mass.:
417.4604
SMILES:
CC(C)CNC(=O)c1c(N)n(Cc2ccc3OCOc3c2)c2nc3ccccc3nc12
Structure:
Search PDB for entries with ligand similarity: