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Target
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
Ligand
BDBM48036
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of PP5: fluorescence-based biochemical high throughput dose response assay for inhibitors of Protein Phosphatase 1 (PP1)
IC50
22658±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of PP5: fluorescence-based biochemical high throughput dose response assay for inhibitors of Protein Phosphatase 1 (PP1) PubChem Bioassay (2010)[AID] 
Target
Name:
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
Synonyms:
PP-1A | PP1A_HUMAN | PPP1A | PPP1CA | Serine/threonine protein phosphatase PP1-alpha catalytic subunit | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit | protein phosphatase 1, catalytic subunit, alpha isoform 3
Type:
PROTEIN
Mol. Mass.:
37510.66
Organism:
Homo sapiens (Human)
Description:
ChEMBL_197827
Residue:
330
Sequence:
MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK
  
Inhibitor
Name:
BDBM48036
Synonyms:
3-[[(4E)-4-(4-ethylphenyl)sulfonylimino-1-keto-2-naphthyl]amino]benzoic acid | 3-[[(4E)-4-(4-ethylphenyl)sulfonylimino-1-oxidanylidene-naphthalen-2-yl]amino]benzoic acid | 3-[[(4E)-4-(4-ethylphenyl)sulfonylimino-1-oxo-2-naphthalenyl]amino]benzoic acid | 3-[[(4E)-4-(4-ethylphenyl)sulfonylimino-1-oxonaphthalen-2-yl]amino]benzoic acid | MLS000948071 | SMR000620248 | cid_5824727
Type:
Small organic molecule
Emp. Form.:
C25H20N2O5S
Mol. Mass.:
460.502
SMILES:
CCc1ccc(cc1)S(=O)(=O)N=C1C=C(Nc2cccc(c2)C(O)=O)C(=O)c2ccccc12 |w:11.11,t:14|
Structure:
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