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Target
Serine/threonine-protein phosphatase
Ligand
BDBM64795
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical high throughput dose response assay for inhibitors of Protein Phosphatase 5 (PP5)
IC50
37494±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay for inhibitors of Protein Phosphatase 5 (PP5) PubChem Bioassay (2010)[AID] 
Target
Name:
Serine/threonine-protein phosphatase
Synonyms:
H0YDU8_HUMAN | PPP5C | PPP5C protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
55092.68
Organism:
Homo sapiens (Human)
Description:
gi_37589898
Residue:
484
Sequence:
MAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVGRPSSGS
  
Inhibitor
Name:
BDBM64795
Synonyms:
4-O-[5-bromo-3-(4-methoxyphenyl)-7-methyl-2-(2-methylpropyl)-6,8-dioxoisoquinolin-7-yl] 1-O-methyl butanedioate | CMLD004098 | MLS001045834 | O4-[5-bromanyl-3-(4-methoxyphenyl)-7-methyl-2-(2-methylpropyl)-6,8-bis(oxidanylidene)isoquinolin-7-yl] O1-methyl butanedioate | SMR000452731 | butanedioic acid O4-[5-bromo-3-(4-methoxyphenyl)-7-methyl-2-(2-methylpropyl)-6,8-dioxo-7-isoquinolinyl] ester O1-methyl ester | cid_16745758 | succinic acid O4-[5-bromo-2-isobutyl-6,8-diketo-3-(4-methoxyphenyl)-7-methyl-7-isoquinolyl] ester O1-methyl ester
Type:
Small organic molecule
Emp. Form.:
C26H28BrNO7
Mol. Mass.:
546.407
SMILES:
COC(=O)CCC(=O)OC1(C)C(=O)C(Br)=C2C=C(N(CC(C)C)C=C2C1=O)c1ccc(OC)cc1 |c:16,23,t:14|
Structure:
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