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Target
Mu-type opioid receptor
Ligand
BDBM62187
Substrate
n/a
Meas. Tech.
SAR Analysis of Antagonists of the MOR Receptor using an Image-Based Assay
IC50
>32000±n/a nM
Citation
 PubChem, PC SAR Analysis of Antagonists of the MOR Receptor using an Image-Based Assay PubChem Bioassay (2010)[AID] 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM62187
Synonyms:
(phenylmethyl) N-[2,2,2-tris(chloranyl)-1-[(2,4-dimethylphenyl)carbamothioylamino]ethyl]carbamate | MLS-0425689.0001 | N-[2,2,2-trichloro-1-[(2,4-dimethylphenyl)thiocarbamoylamino]ethyl]carbamic acid benzyl ester | N-[2,2,2-trichloro-1-[[(2,4-dimethylanilino)-sulfanylidenemethyl]amino]ethyl]carbamic acid (phenylmethyl) ester | benzyl N-[2,2,2-trichloro-1-[(2,4-dimethylphenyl)carbamothioylamino]ethyl]carbamate | cid_3091259
Type:
Small organic molecule
Emp. Form.:
C19H20Cl3N3O2S
Mol. Mass.:
460.805
SMILES:
Cc1ccc(NC(=S)NC(NC(=O)OCc2ccccc2)C(Cl)(Cl)Cl)c(C)c1
Structure:
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