Reaction Details Report a problem with these data
Target
Trans-activator protein BZLF1
Ligand
BDBM64840
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of PP1: fluorescence-based biochemical high throughput dose response assay to identify inhibitors of Protein Phosphatase 5 (PP5)
IC50
>67047±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of PP1: fluorescence-based biochemical high throughput dose response assay to identify inhibitors of Protein Phosphatase 5 (PP5) PubChem Bioassay (2010)[AID] 
Target
Name:
Trans-activator protein BZLF1
Synonyms:
BZLF1 | BZLF1_EBVB9 | PPP5C protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
26856.37
Organism:
Human herpesvirus 4
Description:
gi_82503229
Residue:
245
Sequence:
MMDPNSTSEDVKFTPDPYQVPFVQAFDQATRVYQDLGGPSQAPLPCVLWPVLPEPLPQGQLTAYHVSTAPTGSWFSAPQPAPENAYQAYAAPQLFPVSDITQNQQTNQAGGEAPQPGDNSTVQTAAAVVFACPGANQGQQLADIGVPQPAPVAAPARRTRKPQQPESLEECDSELEIKRYKNRVASRKCRAKFKQLLQHYREVAAAKSSENDRLRLLLKQMCPSLDVDSIIPRTPDVLHEDLLNF
  
Inhibitor
Name:
BDBM64840
Synonyms:
2-(4-methylpyrazol-1-yl)-4-(piperonylamino)pyrimidine-5-carboxylic acid ethyl ester | 4-(1,3-benzodioxol-5-ylmethylamino)-2-(4-methyl-1-pyrazolyl)-5-pyrimidinecarboxylic acid ethyl ester | MLS000040872 | SMR000044643 | cid_663859 | ethyl 4-(1,3-benzodioxol-5-ylmethylamino)-2-(4-methylpyrazol-1-yl)pyrimidine-5-carboxylate
Type:
Small organic molecule
Emp. Form.:
C19H19N5O4
Mol. Mass.:
381.3853
SMILES:
CCOC(=O)c1cnc(nc1NCc1ccc2OCOc2c1)-n1cc(C)cn1
Structure:
Search PDB for entries with ligand similarity: