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Target
G-protein coupled receptor 35
Ligand
BDBM54304
Substrate
n/a
Meas. Tech.
SAR analysis of compounds that inhibit NOD1 - Set 2
IC50
5950±n/a nM
Citation
 PubChem, PC SAR analysis of compounds that inhibit NOD1 - Set 2 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM54304
Synonyms:
2-[(4-bromo-2,5-dimethyl-phenyl)thio]acetic acid [3-cyano-3-(1,3-dihydrobenzimidazol-2-ylidene)-2-keto-propyl] ester | 2-[(4-bromo-2,5-dimethylphenyl)thio]acetic acid [3-cyano-3-(1,3-dihydrobenzimidazol-2-ylidene)-2-oxopropyl] ester | MLS000374952 | SMR000254306 | [3-cyano-3-(1,3-dihydrobenzimidazol-2-ylidene)-2-oxidanylidene-propyl] 2-(4-bromanyl-2,5-dimethyl-phenyl)sulfanylethanoate | [3-cyano-3-(1,3-dihydrobenzimidazol-2-ylidene)-2-oxopropyl] 2-(4-bromo-2,5-dimethylphenyl)sulfanylacetate | cid_5679921
Type:
Small organic molecule
Emp. Form.:
C21H18BrN3O3S
Mol. Mass.:
472.355
SMILES:
Cc1cc(SCC(=O)OCC(=O)C(C#N)c2nc3ccccc3[nH]2)c(C)cc1Br
Structure:
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