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Target
Streptokinase A
Ligand
BDBM65745
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response Followup to Identify Inhibitors of Streptokinase Expression.
EC50
>500000±0 nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response Followup to Identify Inhibitors of Streptokinase Expression. PubChem Bioassay (2010)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM65745
Synonyms:
BRD-K43069600-001-01-1 | N-[3-cyano-4-(4-methylphenyl)sulfanyl-phenyl]-4-fluoranyl-benzamide | N-[3-cyano-4-(4-methylphenyl)sulfanylphenyl]-4-fluorobenzamide | N-[3-cyano-4-(p-tolylthio)phenyl]-4-fluoro-benzamide | N-[3-cyano-4-[(4-methylphenyl)thio]phenyl]-4-fluorobenzamide | cid_2769158
Type:
Small organic molecule
Emp. Form.:
C21H15FN2OS
Mol. Mass.:
362.42
SMILES:
Cc1ccc(Sc2ccc(NC(=O)c3ccc(F)cc3)cc2C#N)cc1
Structure:
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