Reaction Details Report a problem with these data
Target
Kappa-type opioid receptor
Ligand
BDBM65830
Substrate
n/a
Meas. Tech.
SAR analysis of Agonists of the Kappa Opioid Receptor (KOR) using an Image-Based Assay - Set 2
EC50
>32000±n/a nM
Citation
 PubChem, PC SAR analysis of Agonists of the Kappa Opioid Receptor (KOR) using an Image-Based Assay - Set 2 PubChem Bioassay (2010)[AID] 
Target
Name:
Kappa-type opioid receptor
Synonyms:
K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42648.76
Organism:
Homo sapiens (Human)
Description:
P41145
Residue:
380
Sequence:
MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRVRNTVQDPAYLRDIDGMNKPV
  
Inhibitor
Name:
BDBM65830
Synonyms:
4-[[(4-methylphenyl)sulfonylamino]methyl]-N-[3-[(phenylmethyl)-propan-2-yl-amino]propyl]benzamide | 4-[[(4-methylphenyl)sulfonylamino]methyl]-N-[3-[(phenylmethyl)-propan-2-ylamino]propyl]benzamide | KSC-5-249 | KUC103906N | N-[3-[benzyl(isopropyl)amino]propyl]-4-[(tosylamino)methyl]benzamide | N-[3-[benzyl(propan-2-yl)amino]propyl]-4-[[(4-methylphenyl)sulfonylamino]methyl]benzamide | cid_20968607
Type:
Small organic molecule
Emp. Form.:
C28H35N3O3S
Mol. Mass.:
493.661
SMILES:
CC(C)N(CCCNC(=O)c1ccc(CNS(=O)(=O)c2ccc(C)cc2)cc1)Cc1ccccc1
Structure:
Search PDB for entries with ligand similarity: