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Target
Kappa-type opioid receptor
Ligand
BDBM65835
Substrate
n/a
Meas. Tech.
SAR analysis of small molecule agonists of the kappa opioid receptor via a luminescent beta-arrestin assay - Set 2
EC50
>20000±n/a nM
Citation
 PubChem, PC SAR analysis of small molecule agonists of the kappa opioid receptor via a luminescent beta-arrestin assay - Set 2 PubChem Bioassay (2010)[AID] 
Target
Name:
Kappa-type opioid receptor
Synonyms:
K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42648.76
Organism:
Homo sapiens (Human)
Description:
P41145
Residue:
380
Sequence:
MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRVRNTVQDPAYLRDIDGMNKPV
  
Inhibitor
Name:
BDBM65835
Synonyms:
2-[[oxo(3-pyridinyl)methyl]-(thiophen-2-ylmethyl)amino]acetic acid methyl ester | 2-[nicotinoyl(2-thenyl)amino]acetic acid methyl ester | KSC-5-182A | KUC103859N | cid_44483223 | methyl 2-[pyridin-3-ylcarbonyl(thiophen-2-ylmethyl)amino]ethanoate | methyl 2-[pyridine-3-carbonyl(thiophen-2-ylmethyl)amino]acetate
Type:
Small organic molecule
Emp. Form.:
C14H14N2O3S
Mol. Mass.:
290.338
SMILES:
COC(=O)CN(Cc1cccs1)C(=O)c1cccnc1
Structure:
Search PDB for entries with ligand similarity: