Reaction Details Report a problem with these data
Target
Interleukin-8
Ligand
BDBM62334
Substrate
n/a
Meas. Tech.
SAR analysis of Tumor necrosis factor alpha (TNF-alpha) induced IL-8 secretion in MCF-7/NOD1 cells - Set 2
IC50
19840±1400 nM
Citation
 PubChem, PC SAR analysis of Tumor necrosis factor alpha (TNF-alpha) induced IL-8 secretion in MCF-7/NOD1 cells - Set 2 PubChem Bioassay (2010)[AID] 
Target
Name:
Interleukin-8
Synonyms:
CXCL8 | IL8 | IL8_HUMAN | MDNCF-a | interleukin 8 precursor
Type:
PROTEIN
Mol. Mass.:
11104.05
Organism:
Homo sapiens (Human)
Description:
ChEMBL_577736
Residue:
99
Sequence:
MTSKLAVALLAAFLISAALCEGAVLPRSAKELRCQCIKTYSKPFHPKFIKELRVIESGPHCANTEIIVKLSDGRELCLDPKENWVQRVVEKFLKRAENS
  
Inhibitor
Name:
BDBM62334
Synonyms:
1-[(4-chlorophenyl)methyl]-2-benzimidazolamine | 1-[(4-chlorophenyl)methyl]benzimidazol-2-amine | MLS-0425658.0001 | [1-(4-chlorobenzyl)benzimidazol-2-yl]amine | cid_743900
Type:
Small organic molecule
Emp. Form.:
C14H12ClN3
Mol. Mass.:
257.718
SMILES:
Nc1nc2ccccc2n1Cc1ccc(Cl)cc1
Structure:
Search PDB for entries with ligand similarity: