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Target
NADPH oxidase 1
Ligand
BDBM65838
Substrate
n/a
Meas. Tech.
Late stage results from the probe development effort to identify inhibitors of (NADPH oxidase 1) NOX1: Xanthine Oxidase
IC50
11100±n/a nM
Citation
 PubChem, PC Late stage results from the probe development effort to identify inhibitors of (NADPH oxidase 1) NOX1: Xanthine Oxidase PubChem Bioassay (2010)[AID] 
Target
Name:
NADPH oxidase 1
Synonyms:
MOX-1 | MOX1 | Mitogenic oxidase 1 | NADH/NADPH mitogenic oxidase subunit P65-MOX | NOH-1 | NOH1 | NOX-1 | NOX1 | NOX1_HUMAN
Type:
PROTEIN
Mol. Mass.:
64890.44
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792877
Residue:
564
Sequence:
MGNWVVNHWFSVLFLVVWLGLNVFLFVDAFLKYEKADKYYYTRKILGSTLACARASALCLNFNSTLILLPVCRNLLSFLRGTCSFCSRTLRKQLDHNLTFHKLVAYMICLHTAIHIIAHLFNFDCYSRSRQATDGSLASILSSLSHDEKKGGSWLNPIQSRNTTVEYVTFTSIAGLTGVIMTIALILMVTSATEFIRRSYFEVFWYTHHLFIFYILGLGIHGIGGIVRGQTEESMNESHPRKCAESFEMWDDRDSHCRRPKFEGHPPESWKWILAPVILYICERILRFYRSQQKVVITKVVMHPSKVLELQMNKRGFSMEVGQYIFVNCPSISLLEWHPFTLTSAPEEDFFSIHIRAAGDWTENLIRAFEQQYSPIPRIEVDGPFGTASEDVFQYEVAVLVGAGIGVTPFASILKSIWYKFQCADHNLKTKKIYFYWICRETGAFSWFNNLLTSLEQEMEELGKVGFLNYRLFLTGWDSNIVGHAALNFDKATDIVTGLKQKTSFGRPMWDNEFSTIATSHPKSVVGVFLCGPRTLAKSLRKCCHRYSSLDPRKVQFYFNKENF
  
Inhibitor
Name:
BDBM65838
Synonyms:
(2-piperidin-1-ylphenyl) 3-chloranyl-1-benzothiophene-2-carboxylate | (2-piperidin-1-ylphenyl) 3-chloro-1-benzothiophene-2-carboxylate | 3-chloro-1-benzothiophene-2-carboxylic acid [2-(1-piperidinyl)phenyl] ester | 3-chlorobenzothiophene-2-carboxylic acid (2-piperidinophenyl) ester | SR-01000631630-1 | cid_2812902
Type:
Small organic molecule
Emp. Form.:
C20H18ClNO2S
Mol. Mass.:
371.88
SMILES:
Clc1c(sc2ccccc12)C(=O)Oc1ccccc1N1CCCCC1
Structure:
Search PDB for entries with ligand similarity: