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Target
Glucose-6-phosphate 1-dehydrogenase
Ligand
BDBM61989
Substrate
n/a
Meas. Tech.
G6DPH counterscreen for TbHK1 inhibitors - Analogues series
IC50
>25000±n/a nM
Citation
 PubChem, PC G6DPH counterscreen for TbHK1 inhibitors - Analogues series PubChem Bioassay (2010)[AID] 
Target
Name:
Glucose-6-phosphate 1-dehydrogenase
Synonyms:
G6PD_LEUME | glucose-6-phosphate dehydrogenase | zwf
Type:
Enzyme Catalytic Domain
Mol. Mass.:
54421.26
Organism:
Leuconostoc mesenteroides
Description:
gi_149631
Residue:
486
Sequence:
MVSEIKTLVTFFGGTGDLAKRKLYPSVFNLYKKGYLQKHFAIVGTARQALNDDEFKQLVRDSIKDFTDDQAQAEAFIEHFSYRAHDVTDAASYAVLKEAIEEAADKFDIDGNRIFYMSVAPRFFGTIAKYLKSEGLLADTGYNRLMIEKPFGTSYDTAAELQNDLENAFDDNQLFRIDHYLGKEMVQNIAALRFGNPIFDAAWNKDYIKNVQVTLSEVLGVEERAGYYDTAGALLDMIQNHTMQIVGWLAMEKPESFTDKDIRAAKNAAFNALKIYDEAEVNKYFVRAQYGAGDSADFKPYLEELDVPADSKNNTFIAGELQFDLPRWEGVPFYVRSGKRLAAKQTRVDIVFKAGTFNFGSEQEAQEAVLSIIIDPKGAIELKLNAKSVEDAFNTRTIDLGWTVSDEDKKNTPEPYERMIHDTMNGDGSNFADWNGVSIAWKFVDAISAVYTADKAPLETYKSGSMGPEASDKLLAANGDAWVFKG
  
Inhibitor
Name:
BDBM61989
Synonyms:
4-chloro-2-(p-anisoylamino)benzoic acid methyl ester | 4-chloro-2-[[(4-methoxyphenyl)-oxomethyl]amino]benzoic acid methyl ester | KSC-6-265 | KUC105792N | cid_44443674 | methyl 4-chloranyl-2-[(4-methoxyphenyl)carbonylamino]benzoate | methyl 4-chloro-2-[(4-methoxybenzoyl)amino]benzoate
Type:
Small organic molecule
Emp. Form.:
C16H14ClNO4
Mol. Mass.:
319.74
SMILES:
COC(=O)c1ccc(Cl)cc1NC(=O)c1ccc(OC)cc1
Structure:
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